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KMID : 0377619870520120765
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Korean Jungang Medical Journal
1987 Volume.52 No. 12 p.765 ~ p.769
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Clinical Effect of Ceftezole in Neurosurgical Patients
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이익모/Lee, Ik-Mo
박순필/김상진/도종웅/Park, Soon-Phil/Kim, Sang Sin/Doh, Jong-Oung
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Abstract
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Ceftezole is a new cephalosporin derivative which was born at Fujisawa research labora-tories on 1975. It. is known as broad-spectrum antibiotics especially sensitive to E. coil, Kleosiella spp. Staphylococcus, Streptococcus, Salmonella, Shigella etc., and known as anti-biotics of wide safety range.
To study the clinical effect of ceftezole on the infected patients of neurosurgery, we administered ceftezole as first antibiotics before the microorganisms and sensitivities were identified.
The results were as follows:
1) Without the identification of microorganisms and sensitivities, ceftezole was ad-ministered as first drug and there was clinical improvement of 76% of all cases.
2) When we compared microorganisms between the pretreatment and post treatment, S. aureus, E. coil, ?-streptococcus, peptostreptococcus were lightly sensitive to ceftezole.
3) There were no specific side effects on administering ceftezole.
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KEYWORD
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